A contained specimen of SCP Safe Special Containment Procedures: SCP is to be kept in a secured storage locker in Research Sector when not in use. Testing Chamber A a standard humanoid containment unit and B modified to serve as a stable are to be maintained for the purposes of experimentation involving SCP
Used with permission As our castaway flag testifies, natural dyes offer a fairly limited range of colours. They were only present in small amounts and their extraction was often inefficient, so they were usually expensive.
The Dye synthesise textile industry of the 19th century created a need to manufacture larger quantities of cheaper and more versatile alternatives.
Inyear-old Perkin was experimenting in his home laboratory, trying to synthesise the anti-malarial drug quinine found nowadays in tonic water. On testing its solubility, he serendipitously discovered that alcohol extracted a purple colour, which readily dyed silk, and was much more stable in sunlight than any other natural purple dye then in use.
Initially regarded as a useless and filthy nuisance, coal tar turned out to offer an unimaginably rich treasure trove of chemicals. He patented this first synthetic dye in Augustand set about manufacturing it on an industrial scale.
Perkin had to develop large-scale production methods for his starting materials, and to do this he built a factory at Greenford Green in Middlesex. At first he called the dye aniline purple, but, following its success in France, it was renamed mauve or mauveineafter the French word for the purple mallow flower.
Used with permission A technique was developed to apply the dye to cotton fabrics and soon everyone was using it. It was a sensation. Fifty years after his discovery of mauve, he was knighted for his contribution to the British chemical industry.
His achievement was not just the discovery of the dye but its development and exploitation. Chemical research can give rise to useful and valuable materials. Co-operation between manufacturers and users is necessary for progress, and with the right product, chemical manufacture could be commercially viable.
Chemists and industrialists everywhere except Britain it seemed were quick to see the possibilities opened up by Perkin.
The discovery of mauve sparked an international race to produce other synthetic dyes from the myriad chemicals in coal tar.
Research was directed towards determining the structures of natural dyes that could then be synthesised in the laboratory, and subsequently manufactured on an industrial scale.
In that year, alizarin was shown chemically to be derived from the hydrocarbon anthracene, obtained, of course, from coal tar. Although the structure of anthracene itself was not known at the time, a starting material for the laboratory synthesis of alizarin was now available.
As a result, the industry producing the natural dye was killed off almost overnight. The demise of naturally derived indigo was equally dramatic.
A few years later, the Indian indigo trade was dead. Almost all the indigo used from then until now has been synthetically derived. Only for a short time during the First World War was trade in the natural dye revived, but it succumbed almost immediately in the post-war period.
In his search for antiseptic substances that could be used to treat bacterial infections, a German physician, Paul Ehrlich, discovered that one of the dyes he used for staining his microscope slides actually killed bacteria.
He found that the yellow dye flavine killed the germs responsible for abscesses. This led to the development of a wide range of useful drugs, all derived from chemicals found in coal tar. Ironically, several of the chemists employed by these companies had learned their trade with British dye manufacturers before returning to Germany.
The British government had chosen to neglect the infant dye industry, and instead concentrated its support on the well-established textile industry. At the outbreak of the First World War, the only khaki dye available for British army uniforms was manufactured in Germany and had to be imported secretly!AnaSpec provides integrated proteomics solutions, including peptides, antibodies, fluorescent dyes & probes, assay kits, amino acids, solid phase synthesis resins and reagents; provides custom services in peptide synthesis, antibody production, assay development, and analytical validation.
Indocyanine green (ICG) is a near-infrared dye that has been used in the clinic for retinal angiography, and defining cardiovascular and liver function for over 50 years. SYNTHESIS OF NEAR-INFRARED HEPTAMETHINE CYANINE DYES by JAMIE L. GRAGG Under the Direction of Dr. Maged M. Henary ABSTRACT Carbocyanine dyes are organic compounds containing chains of conjugated methine.
A Useful Grignard Reaction: The Synthesis of Dyes Chemistry L Objective: To synthesize and use two dyes, malachite green and crystal violet, prepared from 4-bromo- N,N-dimethylaniline. Background: Organometallic compounds are compounds that contain carbon-metal webkandii.comrd reagents, RMgX, are among the most versatile organic chemistry reagents.
Carry out a microscale organic synthesis to produce indigo dye. Hands-on practical activities or ideas for front of class demonstrations Hands-on practical activities or ideas for front of class demonstrations.
Synthesise of ZnO nano particle as an alternative catalyst for Photocatalytic degradation of brilliant red azo dye Jayamadhava P.
1, Sudhakara A. 3, *, Ramesha S. 2, Nataraja G. 3.