This article has been cited by other articles in PMC. Abstract Background Regression analysis is an important statistical method for the analysis of medical data. It enables the identification and characterization of relationships among multiple factors.

Multiple linear regression analysis is a widely applied technique. In this section we showed here how it can be used to assess and account for confounding and to assess effect modification.

The techniques we described can be extended to adjust for several confounders simultaneously and to investigate more complex effect modification e. There is an important distinction between confounding and effect modification.

Confounding is a distortion of an estimated association caused by an unequal distribution of another risk factor. When there is confounding, we would like to account for it or adjust for it in order to estimate the association without distortion.

In Linear regression analysis women, effect modification is a biological phenomenon in which the magnitude of association is differs at different levels of another factor, e.

In the example, present above it would be in inappropriate to pool the results in men and women. Instead, the goal should be to describe effect modification and report the different effects separately. There are many other applications of multiple regression analysis.

A popular application is to assess the relationships between several predictor variables simultaneously, and a single, continuous outcome. For example, it may be of interest to determine which predictors, in a relatively large set of candidate predictors, are most important or most strongly associated with an outcome.

It is always important in statistical analysis, particularly in the multivariable arena, that statistical modeling is guided by biologically plausible associations. Regression models can also accommodate categorical independent variables.

The module on Hypothesis Testing presented analysis of variance as one way of testing for differences in means of a continuous outcome among several comparison groups. Regression analysis can also be used. However, the investigator must create indicator variables to represent the different comparison groups e.

The set of indicator variables also called dummy variables are considered in the multiple regression model simultaneously as a set independent variables. This categorical variable has six response options. To create the set of indicators, or set of dummy variables, we first decide on a reference group or category.

In this example, the reference group is the racial group that we will compare the other groups against.

Indicator variable are created for the remaining groups and coded 1 for participants who are in that group e. The example below uses an investigation of risk factors for low birth weight to illustrates this technique as well as the interpretation of the regression coefficients in the model.There are many techniques for regression analysis, but here we will consider linear regression.

Linear regression In the Linear regression, dependent variable(Y) is the linear combination of the independent variables(X). Linear regression is the most basic and commonly used predictive analysis.

Regression estimates are used to describe data and to explain the relationship between one dependent variable and one or more independent variables. At the center of the regression analysis is the task of fitting a single. Linear regression is the most basic and commonly used predictive analysis.

Regression estimates are used to describe data and to explain the relationship between one dependent variable and one or more independent variables. At the center of the regression analysis is the task of fitting a single. Combining a modern, data-analytic perspective with a focus on applications in the social sciences, the Third Edition of Applied Regression Analysis and Generalized Linear Models provides in-depth coverage of regression analysis, generalized linear models, and closely related methods, such as bootstrapping and missing webkandii.comd throughout, this Third Edition includes new chapters on .

There are many techniques for regression analysis, but here we will consider linear regression. Linear regression In the Linear regression, dependent variable(Y) is the linear combination of the independent variables(X). Linear regression is a great starting place when you want to predict a number, such as profit, cost, or sales.

In simple linear regression, there is only one independent variable .

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Linear Regression Analysis